Helen Stölting

 Helen Stölting – Postdoc

I recently completed my PhD, which was supervised by Clare and Sejal and funded by the British Lung Foundation and am currently staying on as a postdoc working on the Breathing Together study. The main focus of my research is to investigate the role of EGFR signalling in driving pathology of early life allergic airway disease. In addition, I also take an interest in airway epithelial cells and how they respond to respiratory virus infection or allergen exposure.

Originally from Germany, I did my BSc in Molecular Biomedicine at the University of Bonn, from which I graduated in 2016, and then spent a year doing various internships at Roehampton University (London), Bayer Pharmaceuticals (Berlin) and Charité (Berlin). I came to Imperial in 2017 for my MSc in Immunology and joined the Lloyd lab for my master research project on “Regulation of Immune Responses during Allergic Airway Disease by T Cell-Derived Interleukin-10 and Airway Macrophages”. Having had a great time during my MSc project, I decided to stay on for my PhD, which I started in October 2018 and finished at the end of 2022.

helen.stoelting17@imperial.ac.uk

0000-0002-7830-2776

@HelenIsInTheLab

Publications

  • Joulia, R., Puttur, F., Stölting, H., Entwistle, L.J., Voitovich, A., Al-Sahaf, M., Bonner, K., Scotney, E., Molyneaux, P.L., Hewitt, R.J., Walker, S.A., Yates, L.L., Saglani, S., Lloyd, C.M. (2023) Adventitial mast cell activation disrupts endothelial cell/pericyte interactions during early life allergic asthma. bioRxiv 2023.03.07.529253. https://doi.org/10.1101/2023.03.07.529253
  • de Carvalho, E., Bartok, E., Stölting, H., Baubak, B., Leptin, M. (2022). Revisiting the origin of interleukin 1 in anamniotes and sub-functionalization of interleukin 1 in amniotes. Open Biol. 12, 220049-220049. https://doi.org/10.1098/rsob.220049
  • Stölting, H., Baillon, L., Frise, R., Bonner, K., Hewitt, R.J., Molyneaux, P.L., Gore, M.L., Breathing Together Consortium, Barclay, W.S., Saglani, S., Lloyd, C.M. (2022). Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1. Mucosal Immunol 15, 952–963. https://doi.org/10.1038/s41385-022-00545-4
  • Stölting, H. and Lloyd, C.M. (2022). Pseudomonas aeruginosa: a pathogen making itself at home. Trends Immunol. 43, 497-499. https://doi.org/10.1016/j.it.2022.05.002
  • Branchett, W.J., Cook, J., Oliver, R.A., Bruno, N., Walkers, S.A., Stölting, H., Mack, M., O’Garra, A., Saglani, S., Lloyd, C.M. (2021). Airway macrophage-intrinsic TGF-β1 controls pulmonary mononuclear phagocyte accumulation and type 2 immunity during early life allergen exposure. J Allergy Clin Immunol. 147, 1892-1906. https://doi.org/10.1016/j.jaci.2021.01.026
  • Branchett, W.J., Stölting, H., Oliver, R.A., Walker, S.A., Puttur, F., Gregory, L.G., Gabrysova, L., Wilson, M.S., O’Garra, A., and Lloyd, C.M. (2019). A T cell-myeloid IL-10 axis regulates pathogenic IFN-gamma-dependent immunity in a mouse model of type 2-low asthma. J Allergy Clin Immunol. 145, 666-678. https://doi.org/10.1016/j.jaci.2019.08.006
  • Bravo-Santano, N., Stölting, H., Cooper, F., Bileckaja, N., Majstorovic, A., Ihle, N., Mateos, L.M., Calle, Y., Behrends, V., and Letek, M. (2019). Host-directed kinase inhibitors act as novel therapies against intracellular Staphylococcus aureus. Scientific Reports 9, 4876. https://doi.org/10.1038/s41598-019-41260-8